AAN 2012

Comparison of Risk Factors between First Ischemic Stroke and Myocardial Infarction at a Medical Center in Buenos Aires City, Argentina

Emilia Gatto, Ines Ballarino, Gabriel Persi, Sabrina Antongiovanni, Matías Failo and Virginia Parisi

^{Sanatorio de la Trinidad Mitre Buenos Aires Argentina}

Objective: to analyze the risk factors (RF) distribution in first stroke or MI in a population with similar socioeconomic characteristics and access to health resources.

Background Ischemic Stroke (IS) and Myocardial Infarction (MI) share their main classical risk factors (RF). These conditions, however, could predispose in a different manner to suffer either IS or MI.

Design/Methods: We prospectively collected data from patients diagnosed with first IS or MI, who were admitted at our center in Buenos Aires, Argentina, from January to June 2011. We analyzed demographic characteristics, classical risk factors such as diabetes, hypertension and dyslipidemia, smoking, and usual and previous medication and event features. Descriptive statistics and nonparametric tests were used.

Results: In this period of time 48 patients with IS and 17 with IM were evaluated in our institution. Sixteen patients with their first MI and 25 with a first IS were included for the analysis. Ischemic stroke patients were slightly older than MI patients (median 60 vs. 73 years, p: 0.0382). A male/female ratio of 7/1 was observed in the MI group and 1.5/1 in IS patients. This difference in sex distribution did not reach statistical significance. Current smoking/ever smoking was more prevalent in the MI group (32% vs 87.5%, P: 0.001), and dyslipidemia was slightly more frequent in MI patients (24 vs 62.5%, p: 0.022). We did not find differences in the prevalence of diabetes, hypertension and previous or usual medication (aspirin, statins, ACEI and ARA) between groups.

Conclusions: As described in the literature, classical RF distribution was different between first Ischemic Stroke and first Myocardial Infarction. Based on these results, a second study with a larger number of patients is currently underway in search of non-conventional RF in both groups of patients.

Neurology April 25, 2012; 78(Meeting Abstracts 1): P05.222